Disease: Mammary Tumorigenesis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDC25A P30304 cell division cycle 25A Enzyme 0.84 0.564 0.615
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
EREG O14944 epiregulin Signaling 1.2E-05 0.554 0.692
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
NCOA3 Q9Y6Q9 nuclear receptor coactivator 3 Kinase 0.54 0.522 0.654
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
S100A4 P26447 S100 calcium binding protein A4 Calcium-binding protein 6.2E-03 0.448 0.769