Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
IL10 | P22301 | interleukin 10 | 5.9E-03 | 0.281 | 0.923 | |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
SERPINE1 | P05121 | serpin family E member 1 | Enzyme modulator | 4.4E-02 | 0.359 | 0.885 |
FAS | P25445 | Fas cell surface death receptor | 0.81 | 0.372 | 0.923 | |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
GSTM1 | P09488 | glutathione S-transferase mu 1 | 2.1E-03 | 0.380 | 0.923 | |
KRT20 | P35900 | keratin 20 | 9.1E-11 | 0.388 | 0.846 | |
GSTT1 | P30711 | glutathione S-transferase theta 1 | 1.5E-04 | 0.393 | 0.923 | |
PGR | P06401 | progesterone receptor | Nuclear receptor | 5.1E-02 | 0.426 | 0.885 |
EPCAM | P16422 | epithelial cell adhesion molecule | 1.3E-07 | 0.451 | 0.885 | |
VEGFC | P49767 | vascular endothelial growth factor C | Signaling | 0.50 | 0.459 | 0.769 |
RARA | P10276 | retinoic acid receptor alpha | Nuclear receptor | 0.96 | 0.470 | 0.846 |
KRT19 | P08727 | keratin 19 | 4.3E-03 | 0.460 | 0.731 | |
SIRT3 | Q9NTG7 | sirtuin 3 | Epigenetic regulator | 1.6E-04 | 0.488 | 0.731 |
FGFR4 | P22455 | fibroblast growth factor receptor 4 | Kinase | 7.2E-13 | 0.490 | 0.769 |
CDK1 | P06493 | cyclin dependent kinase 1 | Kinase | 0.99 | 0.482 | 0.808 |
BCS1L | Q9Y276 | BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone | 4.7E-13 | 0.534 | 0.808 | |
HTRA1 | Q92743 | HtrA serine peptidase 1 | Enzyme | 4.9E-04 | 0.532 | 0.692 |
POU1F1 | P28069 | POU class 1 homeobox 1 | 4.5E-02 | 0.548 | 0.654 |