Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
COX2 | P00403 | cytochrome c oxidase subunit II | Enzyme | 0.352 | 0.962 | |
SPP1 | P10451 | secreted phosphoprotein 1 | 2.1E-06 | 0.353 | 0.885 | |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
SERPINE1 | P05121 | serpin family E member 1 | Enzyme modulator | 4.4E-02 | 0.359 | 0.885 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
MTCO2P12 | MT-CO2 pseudogene 12 | 0.368 | 0.962 | |||
CAV1 | Q03135 | caveolin 1 | Enzyme modulator | 8.3E-03 | 0.388 | 0.885 |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
COX8A | P10176 | cytochrome c oxidase subunit 8A | Enzyme | 0.12 | 0.400 | 0.846 |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
CEACAM5 | P06731 | CEA cell adhesion molecule 5 | 4.2E-10 | 0.420 | 0.846 | |
JAG1 | P78504 | jagged canonical Notch ligand 1 | 1.00 | 0.429 | 0.808 | |
BRD4 | O60885 | bromodomain containing 4 | Epigenetic regulator | 1.00 | 0.446 | 0.885 |
EPCAM | P16422 | epithelial cell adhesion molecule | 1.3E-07 | 0.451 | 0.885 | |
PTK2B | Q14289 | protein tyrosine kinase 2 beta | Kinase | 0.94 | 0.448 | 0.808 |