Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
NR1H4 Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 9.4E-04 0.513 0.808
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PRKCD Q05655 protein kinase C delta Kinase 1.00 0.480 0.846
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
MOK Q9UQ07 MOK protein kinase Kinase 8.8E-22 0.476 0.769
RIPK3 Q9Y572 receptor interacting serine/threonine kinase 3 Kinase 1.2E-14 0.497 0.885
MLKL Q8NB16 mixed lineage kinase domain like pseudokinase Kinase 2.1E-14 0.570 0.731
GLP1R P43220 glucagon like peptide 1 receptor G-protein coupled receptor 0.29 0.471 0.846
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
GPBAR1 Q8TDU6 G protein-coupled bile acid receptor 1 G-protein coupled receptor 1.4E-09 0.548 0.731
OR10A4 Q9H209 olfactory receptor family 10 subfamily A member 4 G-protein coupled receptor 1.7E-05 0.540 0.808
SETMAR Q53H47 SET domain and mariner transposase fusion gene Epigenetic regulator 1.0E-04 0.617 0.692
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
PTPA Q15257 protein phosphatase 2 phosphatase activator Enzyme modulator 0.99 0.480 0.846
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
ADH1C P00326 alcohol dehydrogenase 1C (class I), gamma polypeptide Enzyme 0.547 0.731
AHCY P23526 adenosylhomocysteinase Enzyme 3.6E-02 0.582 0.692