Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CXCR2 P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 1.4E-02 0.445 0.923
CYBB P04839 cytochrome b-245 beta chain Ion channel 1.00 0.452 0.885
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
ENHO Q6UWT2 energy homeostasis associated 0.11 0.599 0.769
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846
FGF21 Q9NSA1 fibroblast growth factor 21 Signaling 2.9E-02 0.485 0.769
FOXO1 Q12778 forkhead box O1 1.00 0.433 0.846
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
GCG P01275 glucagon 3.5E-02 0.431 0.885
GDF15 Q99988 growth differentiation factor 15 Signaling 3.0E-07 0.429 0.808
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
GHR P10912 growth hormone receptor Signaling 8.4E-05 0.490 0.846
GLP1R P43220 glucagon like peptide 1 receptor G-protein coupled receptor 0.29 0.471 0.846
GNMT Q14749 glycine N-methyltransferase 2.8E-03 0.626 0.462
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846