Disease: Autoinflammatory disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADA2 Q9NZK5 adenosine deaminase 2 Enzyme 8.1E-08 0.545 0.846
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885
CGAS Q8N884 cyclic GMP-AMP synthase 8.7E-09 0.705 0.538
DNASE2 O00115 deoxyribonuclease 2, lysosomal Enzyme 4.5E-04 0.700 0.462
ERAP1 Q9NZ08 endoplasmic reticulum aminopeptidase 1 Enzyme 2.1E-26 0.556 0.692
IFIH1 Q9BYX4 interferon induced with helicase C domain 1 7.0E-44 0.471 0.808
IFNA1 P01562 interferon alpha 1 0.371 0.923
IFNA13 P01562 interferon alpha 13 0.374 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL1RL2 Q9HB29 interleukin 1 receptor like 2 Receptor 3.5E-11 0.682 0.500
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
IL36RN Q9UBH0 interleukin 36 receptor antagonist 3.4E-08 0.638 0.538
IL6 P05231 interleukin 6 0.32 0.248 0.962
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
MVK Q03426 mevalonate kinase Kinase 0.17 0.576 0.731
NLRC4 Q9NPP4 NLR family CARD domain containing 4 9.9E-12 0.556 0.769
NLRP1 Q9C000 NLR family pyrin domain containing 1 5.0E-19 0.502 0.769
NLRP12 P59046 NLR family pyrin domain containing 12 3.6E-28 0.569 0.846
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
OTULIN Q96BN8 OTU deubiquitinase with linear linkage specificity 0.22 0.751 0.346
PLCG2 P16885 phospholipase C gamma 2 Enzyme 1.00 0.588 0.808
PSMB8 P28062 proteasome 20S subunit beta 8 2.2E-02 0.533 0.808