Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
FOXO3 O43524 forkhead box O3 0.99 0.431 0.808
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
COMP P49747 cartilage oligomeric matrix protein 1.3E-09 0.503 0.808
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731
SDHC Q99643 succinate dehydrogenase complex subunit C 2.0E-04 0.517 0.846
KLLN B2CW77 killin, p53 regulated DNA replication inhibitor 5.1E-03 0.578 0.654
SEC23B Q15437 SEC23 homolog B, COPII coat complex component Enzyme modulator 6.1E-20 0.579 0.692
SMAD9 O15198 SMAD family member 9 Transcription factor 6.4E-05 0.666 0.308
LYPD1 Q8N2G4 LY6/PLAUR domain containing 1 5.5E-04 0.805 0.346