Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
TSC1 Q92574 TSC complex subunit 1 1.00 0.440 0.808
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
NF2 P35240 neurofibromin 2 1.00 0.468 0.885
DICER1 Q9UPY3 dicer 1, ribonuclease III Enzyme 1.00 0.446 0.846
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
FH P07954 fumarate hydratase Enzyme 8.8E-02 0.489 0.846
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
ETV5 P41161 ETS variant transcription factor 5 Transcription factor 1.00 0.565 0.731
POT1 Q9NUX5 protection of telomeres 1 Nucleic acid binding 0.85 0.560 0.731
KIAA1549 Q9HCM3 KIAA1549 0.99 0.615 0.346