Disease: Common Variable Immunodeficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IFNA1 P01562 interferon alpha 1 0.371 0.923
IFNA13 P01562 interferon alpha 13 0.374 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TRBV20OR9-2 T cell receptor beta variable 20/OR9-2 (non-functional) 0.403 0.923
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CD14 P08571 CD14 molecule 4.9E-05 0.392 0.885
CD28 P10747 CD28 molecule 0.36 0.436 0.885
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885
HLA-DRB3 P79483 major histocompatibility complex, class II, DR beta 3 Immune response 0.570 0.885
IL2 P60568 interleukin 2 0.48 0.336 0.885
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885