Disease: Mitral Valve Prolapse Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
LMNA P02545 lamin A/C 1.00 0.384 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
FLNA P21333 filamin A 1.00 0.419 0.846
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846
LIMK1 P53667 LIM domain kinase 1 Kinase 1.00 0.488 0.731
RYR1 P21817 ryanodine receptor 1 Ion channel 1.6E-29 0.489 0.808
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
ENPP1 P22413 ectonucleotide pyrophosphatase/phosphodiesterase 1 Enzyme 5.0E-08 0.498 0.808
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808
SKI P12755 SKI proto-oncogene 1.00 0.503 0.808
RFC2 P35250 replication factor C subunit 2 Enzyme 2.2E-06 0.520 0.769
GTF2IRD1 Q9UHL9 GTF2I repeat domain containing 1 0.90 0.522 0.769