Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MMP2 | P08253 | matrix metallopeptidase 2 | Enzyme | 0.84 | 0.333 | 0.923 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
MUC1 | P15941 | mucin 1, cell surface associated | 1.9E-02 | 0.384 | 0.885 | |
PGR | P06401 | progesterone receptor | Nuclear receptor | 5.1E-02 | 0.426 | 0.885 |
CD40 | P25942 | CD40 molecule | 0.85 | 0.396 | 0.846 | |
ERCC1 | P07992 | ERCC excision repair 1, endonuclease non-catalytic subunit | Enzyme | 1.6E-07 | 0.445 | 0.846 |
F3 | P13726 | coagulation factor III, tissue factor | Receptor | 1.9E-02 | 0.415 | 0.846 |
GLI1 | P08151 | GLI family zinc finger 1 | 7.7E-14 | 0.431 | 0.846 | |
PSMD9 | O00233 | proteasome 26S subunit, non-ATPase 9 | Enzyme modulator | 4.9E-06 | 0.435 | 0.846 |
VIM | P08670 | vimentin | 0.71 | 0.372 | 0.846 | |
MIR145 | microRNA 145 | 0.431 | 0.846 | |||
MIR21 | microRNA 21 | 0.363 | 0.846 | |||
MKI67 | P46013 | marker of proliferation Ki-67 | 1.3E-28 | 0.431 | 0.808 | |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |