Disease: Advanced breast cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FASN P49327 fatty acid synthase Enzyme 1.00 0.474 0.846
GATA3 P23771 GATA binding protein 3 0.90 0.415 0.846
GLS O94925 glutaminase Enzyme 0.96 0.489 0.808
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
LINC-ROR long intergenic non-protein coding RNA, regulator of reprogramming 0.548 0.769
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
MELK Q14680 maternal embryonic leucine zipper kinase Kinase 4.5E-22 0.566 0.577
MIR21 microRNA 21 0.363 0.846
MIR222 microRNA 222 0.486 0.808
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923