Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
MSLN Q13421 mesothelin Extracellular structure 5.9E-25 0.525 0.692
MELK Q14680 maternal embryonic leucine zipper kinase Kinase 4.5E-22 0.566 0.577
FAT2 Q9NYQ8 FAT atypical cadherin 2 6.0E-18 0.792 0.346
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
KDM5B Q9UGL1 lysine demethylase 5B Epigenetic regulator 7.9E-15 0.532 0.731
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846
ME1 P48163 malic enzyme 1 Enzyme 8.2E-14 0.628 0.615
TRIB3 Q96RU7 tribbles pseudokinase 3 Kinase 1.2E-13 0.573 0.692
CIP2A Q8TCG1 cellular inhibitor of PP2A 1.4E-13 0.524 0.808
GABRP O00591 gamma-aminobutyric acid type A receptor subunit pi Ion channel 1.8E-13 0.736 0.462
IL17RB Q9NRM6 interleukin 17 receptor B 4.5E-11 0.601 0.808
FLNB O75369 filamin B 6.1E-10 0.458 0.923
SLC22A3 O75751 solute carrier family 22 member 3 Transporter 7.8E-10 0.531 0.846
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
POSTN Q15063 periostin Signaling 1.1E-09 0.428 0.885
ARHGAP11A Q6P4F7 Rho GTPase activating protein 11A 2.1E-09 0.821 0.308
TRIM21 P19474 tripartite motif containing 21 3.4E-09 0.485 0.808
PINX1 Q96BK5 PIN2 (TERF1) interacting telomerase inhibitor 1 Enzyme modulator 4.6E-09 0.587 0.692
SIRT2 Q8IXJ6 sirtuin 2 Epigenetic regulator 2.3E-08 0.510 0.769
ITK Q08881 IL2 inducible T cell kinase Kinase 3.1E-08 0.555 0.769