Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
VWF | P04275 | von Willebrand factor | Enzyme modulator | 3.2E-25 | 0.408 | 0.885 |
MSLN | Q13421 | mesothelin | Extracellular structure | 5.9E-25 | 0.525 | 0.692 |
MELK | Q14680 | maternal embryonic leucine zipper kinase | Kinase | 4.5E-22 | 0.566 | 0.577 |
FAT2 | Q9NYQ8 | FAT atypical cadherin 2 | 6.0E-18 | 0.792 | 0.346 | |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
EGF | P01133 | epidermal growth factor | 8.5E-17 | 0.357 | 0.923 | |
WWOX | Q9NZC7 | WW domain containing oxidoreductase | Enzyme | 1.2E-15 | 0.453 | 0.808 |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
KDM5B | Q9UGL1 | lysine demethylase 5B | Epigenetic regulator | 7.9E-15 | 0.532 | 0.731 |
GLI1 | P08151 | GLI family zinc finger 1 | 7.7E-14 | 0.431 | 0.846 | |
ME1 | P48163 | malic enzyme 1 | Enzyme | 8.2E-14 | 0.628 | 0.615 |
TRIB3 | Q96RU7 | tribbles pseudokinase 3 | Kinase | 1.2E-13 | 0.573 | 0.692 |
CIP2A | Q8TCG1 | cellular inhibitor of PP2A | 1.4E-13 | 0.524 | 0.808 | |
GABRP | O00591 | gamma-aminobutyric acid type A receptor subunit pi | Ion channel | 1.8E-13 | 0.736 | 0.462 |
IL17RB | Q9NRM6 | interleukin 17 receptor B | 4.5E-11 | 0.601 | 0.808 | |
FLNB | O75369 | filamin B | 6.1E-10 | 0.458 | 0.923 | |
SLC22A3 | O75751 | solute carrier family 22 member 3 | Transporter | 7.8E-10 | 0.531 | 0.846 |
MMP7 | P09237 | matrix metallopeptidase 7 | Enzyme | 1.0E-09 | 0.446 | 0.885 |
POSTN | Q15063 | periostin | Signaling | 1.1E-09 | 0.428 | 0.885 |
ARHGAP11A | Q6P4F7 | Rho GTPase activating protein 11A | 2.1E-09 | 0.821 | 0.308 | |
TRIM21 | P19474 | tripartite motif containing 21 | 3.4E-09 | 0.485 | 0.808 | |
PINX1 | Q96BK5 | PIN2 (TERF1) interacting telomerase inhibitor 1 | Enzyme modulator | 4.6E-09 | 0.587 | 0.692 |
SIRT2 | Q8IXJ6 | sirtuin 2 | Epigenetic regulator | 2.3E-08 | 0.510 | 0.769 |
ITK | Q08881 | IL2 inducible T cell kinase | Kinase | 3.1E-08 | 0.555 | 0.769 |