| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| SPG7 | Q9UQ90 | SPG7 matrix AAA peptidase subunit, paraplegin | Enzyme | 2.0E-36 | 0.436 | 0.885 |
| SPG11 | Q96JI7 | SPG11 vesicle trafficking associated, spatacsin | 1.6E-39 | 0.576 | 0.538 | |
| SPAST | Q9UBP0 | spastin | Cellular structure | 1.00 | 0.579 | 0.577 |
| IFT122 | Q9HBG6 | intraflagellar transport 122 | 2.4E-24 | 0.560 | 0.846 | |
| ATL1 | Q8WXF7 | atlastin GTPase 1 | Enzyme modulator | 0.98 | 0.593 | 0.654 |
| DPY30 | Q9C005 | dpy-30 histone methyltransferase complex regulatory subunit | 0.18 | 0.700 | 0.462 | |
| SPG16 | spastic paraplegia 16 (complicated, X-linked recessive) | 0.722 | 0.423 |