Disease: Progressive sensorineural hearing impairment
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTG1 P63261 actin gamma 1 Cellular structure 4.8E-03 0.477 0.846
COCH O43405 cochlin Receptor 1.2E-07 0.659 0.385
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885
DFNA24 deafness, autosomal dominant 24 0.931 0.115
DIAPH1 O60610 diaphanous related formin 1 0.92 0.623 0.654
EYA4 O95677 EYA transcriptional coactivator and phosphatase 4 4.9E-02 0.604 0.615
GIPC3 Q8TF64 GIPC PDZ domain containing family member 3 Enzyme 9.3E-03 0.780 0.231
GJB2 P29033 gap junction protein beta 2 Cell-cell junction 6.6E-16 0.441 0.846
GJB3 O75712 gap junction protein beta 3 Cell-cell junction 2.2E-03 0.621 0.462
GJB6 O95452 gap junction protein beta 6 Cell-cell junction 1.7E-07 0.528 0.808
GRXCR1 A8MXD5 glutaredoxin and cysteine rich domain containing 1 3.9E-11 0.861 0.115
GSDME O60443 gasdermin E 3.3E-09 0.656 0.423
KCNQ4 P56696 potassium voltage-gated channel subfamily Q member 4 Ion channel 0.47 0.674 0.462
MCM2 P49736 minichromosome maintenance complex component 2 Enzyme 2.6E-05 0.527 0.731
MPZL2 O60487 myelin protein zero like 2 1.1E-12 0.653 0.500
MYH14 Q7Z406 myosin heavy chain 14 4.2E-02 0.663 0.577
MYH9 P35579 myosin heavy chain 9 1.00 0.505 0.808
MYO15A Q9UKN7 myosin XVA Cellular structure 1.3E-56 0.722 0.346
MYO3A Q8NEV4 myosin IIIA Kinase 1.8E-45 0.780 0.269
MYO6 Q9UM54 myosin VI Cellular structure 2.4E-05 0.631 0.731
MYO7A Q13402 myosin VIIA Cellular structure 1.6E-38 0.585 0.423
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
P2RX2 Q9UBL9 purinergic receptor P2X 2 Ion channel 9.7E-13 0.585 0.769
POU3F4 P49335 POU class 3 homeobox 4 0.57 0.633 0.654
SMPX Q9UHP9 small muscle protein X-linked 0.62 0.682 0.500