Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
CD44 | P16070 | CD44 molecule (Indian blood group) | 2.4E-07 | 0.363 | 0.962 | |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
MET | P08581 | MET proto-oncogene, receptor tyrosine kinase | Kinase | 0.97 | 0.380 | 0.846 |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
PDGFRA | P16234 | platelet derived growth factor receptor alpha | Kinase | 1.00 | 0.415 | 0.808 |
CD163 | Q86VB7 | CD163 molecule | Enzyme | 8.3E-04 | 0.427 | 0.846 |
EIF4E | P06730 | eukaryotic translation initiation factor 4E | Nucleic acid binding | 0.94 | 0.448 | 0.846 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
DCN | P07585 | decorin | 0.31 | 0.457 | 0.808 | |
CIB1 | Q99828 | calcium and integrin binding 1 | 3.3E-04 | 0.458 | 0.769 | |
ALDH1A1 | P00352 | aldehyde dehydrogenase 1 family member A1 | Enzyme | 0.95 | 0.460 | 0.846 |
DDIT3 | P35638 | DNA damage inducible transcript 3 | 0.59 | 0.467 | 0.846 | |
EZR | P15311 | ezrin | Cellular structure | 0.18 | 0.476 | 0.808 |
EWSR1 | Q01844 | EWS RNA binding protein 1 | Nucleic acid binding | 1.00 | 0.474 | 0.692 |
SKP2 | Q13309 | S-phase kinase associated protein 2 | 0.96 | 0.492 | 0.808 | |
ASS1 | P00966 | argininosuccinate synthase 1 | Enzyme | 1.5E-09 | 0.523 | 0.731 |
TRIO | O75962 | trio Rho guanine nucleotide exchange factor | Kinase | 1.00 | 0.556 | 0.731 |