Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
POMC | P01189 | proopiomelanocortin | 1.2E-04 | 0.356 | 0.846 | |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
PCNA | P12004 | proliferating cell nuclear antigen | Nucleic acid binding | 0.98 | 0.382 | 0.846 |
SST | P61278 | somatostatin | Signaling | 0.34 | 0.399 | 0.885 |
TYMS | P04818 | thymidylate synthetase | Enzyme | 0.72 | 0.425 | 0.846 |
LGALS1 | P09382 | galectin 1 | Signaling | 4.5E-03 | 0.435 | 0.846 |
ERCC1 | P07992 | ERCC excision repair 1, endonuclease non-catalytic subunit | Enzyme | 1.6E-07 | 0.445 | 0.846 |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
KRT7 | P08729 | keratin 7 | 3.1E-12 | 0.463 | 0.808 | |
AKT2 | P31751 | AKT serine/threonine kinase 2 | Kinase | 0.64 | 0.474 | 0.769 |
EWSR1 | Q01844 | EWS RNA binding protein 1 | Nucleic acid binding | 1.00 | 0.474 | 0.692 |
BCL2L1 | Q07817 | BCL2 like 1 | Signaling | 0.94 | 0.493 | 0.885 |
TAL1 | P17542 | TAL bHLH transcription factor 1, erythroid differentiation factor | Transcription factor | 0.57 | 0.505 | 0.731 |
TOP2A | P11388 | DNA topoisomerase II alpha | 0.99 | 0.497 | 0.731 | |
SCLY | Q96I15 | selenocysteine lyase | Enzyme | 2.3E-09 | 0.530 | 0.731 |
RRM1 | P23921 | ribonucleotide reductase catalytic subunit M1 | Enzyme | 1.00 | 0.552 | 0.692 |