Disease: Delayed speech and language development
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
ASPM Q8IZT6 abnormal spindle microtubule assembly 3.4E-49 0.526 0.769
LAMA2 P24043 laminin subunit alpha 2 Enzyme modulator 2.4E-47 0.553 0.692
VPS13B Q7Z7G8 vacuolar protein sorting 13 homolog B 2.5E-45 0.579 0.769
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
RTTN Q86VV8 rotatin 9.0E-34 0.619 0.654
IFT172 Q9UG01 intraflagellar transport 172 Cellular structure 3.3E-33 0.582 0.654
LAMA1 P25391 laminin subunit alpha 1 3.2E-32 0.582 0.808
PRSS12 P56730 serine protease 12 Enzyme 8.4E-29 0.682 0.308
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
EMC1 Q8N766 ER membrane protein complex subunit 1 6.7E-26 0.700 0.462
ARMC4 Q5T2S8 armadillo repeat containing 4 1.9E-25 0.641 0.615
CEP63 Q96MT8 centrosomal protein 63 Cellular structure 6.2E-25 0.666 0.500
WDR62 O43379 WD repeat domain 62 2.4E-23 0.597 0.615
ALDH7A1 P49419 aldehyde dehydrogenase 7 family member A1 Enzyme 1.4E-22 0.551 0.769
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
ELP2 Q6IA86 elongator acetyltransferase complex subunit 2 4.2E-20 0.716 0.538
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
COG5 Q9UP83 component of oligomeric golgi complex 5 9.8E-20 0.656 0.538
KYNU Q16719 kynureninase Enzyme 4.2E-18 0.617 0.692
BBS2 Q9BXC9 Bardet-Biedl syndrome 2 1.0E-17 0.565 0.654
PMM2 O15305 phosphomannomutase 2 Enzyme 1.4E-17 0.535 0.769
POMT1 Q9Y6A1 protein O-mannosyltransferase 1 4.2E-17 0.525 0.615