Disease: Cognitive changes
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKAP6 Q13023 A-kinase anchoring protein 6 1.00 0.695 0.538
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CTNND2 Q9UQB3 catenin delta 2 Cellular structure 1.00 0.579 0.731
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885
GNAQ P50148 G protein subunit alpha q Enzyme modulator 0.98 0.516 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
NEFL P07196 neurofilament light 0.488 0.769
PNPLA6 Q8IY17 patatin like phospholipase domain containing 6 Enzyme 1.9E-13 0.533 0.769
SLC33A1 O00400 solute carrier family 33 member 1 Transporter 9.9E-05 0.529 0.769
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538