Disease: Pick Disease of the Brain
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
CDC42 P60953 cell division cycle 42 Enzyme modulator 0.79 0.458 0.846
REG1A P05451 regenerating family member 1 alpha 1.3E-05 0.467 0.846
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
VCP P55072 valosin containing protein 1.00 0.469 0.923
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
EWSR1 Q01844 EWS RNA binding protein 1 Nucleic acid binding 1.00 0.474 0.692
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
NEFL P07196 neurofilament light 0.488 0.769
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
GGT1 P19440 gamma-glutamyltransferase 1 Enzyme 7.5E-05 0.496 0.885
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
MSMB P08118 microseminoprotein beta Signaling 1.6E-02 0.498 0.846
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808