Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ALK | Q9UM73 | ALK receptor tyrosine kinase | Kinase | 3.2E-06 | 0.396 | 0.846 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
MGMT | P16455 | O-6-methylguanine-DNA methyltransferase | 1.2E-07 | 0.412 | 0.885 | |
MIR31 | microRNA 31 | 0.471 | 0.769 | |||
MUC16 | Q8WXI7 | mucin 16, cell surface associated | 8.3E-112 | 0.479 | 0.808 | |
PARP1 | P09874 | poly(ADP-ribose) polymerase 1 | 3.3E-04 | 0.389 | 0.923 | |
PDCD1 | Q15116 | programmed cell death 1 | 0.42 | 0.402 | 0.846 | |
STK11 | Q15831 | serine/threonine kinase 11 | Kinase | 0.99 | 0.435 | 0.808 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |