Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
USP18 Q9UMW8 ubiquitin specific peptidase 18 1.5E-03 0.601 0.615
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923
TNFRSF11A Q9Y6Q6 TNF receptor superfamily member 11a 8.8E-03 0.480 0.846
TNFAIP3 P21580 TNF alpha induced protein 3 Enzyme 1.00 0.481 0.808
TREX1 Q9NSU2 three prime repair exonuclease 1 0.58 0.517 0.808
STING1 Q86WV6 stimulator of interferon response cGAMP interactor 1 1.2E-03 0.522 0.769
SLC29A3 Q9BZD2 solute carrier family 29 member 3 Transporter 1.3E-07 0.578 0.769
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
SH3BP2 P78314 SH3 domain binding protein 2 1.2E-11 0.623 0.654
SAA1 P0DJI8 serum amyloid A1 Transporter 1.5E-02 0.513 0.808
SAMHD1 Q9Y3Z3 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 6.5E-13 0.547 0.769
ROS1 P08922 ROS proto-oncogene 1, receptor tyrosine kinase Kinase 1.6E-72 0.439 0.885
RNASEH2C Q8TDP1 ribonuclease H2 subunit C 5.5E-03 0.590 0.731
RNASEH2B Q5TBB1 ribonuclease H2 subunit B 3.3E-09 0.595 0.615
RNASEH2A O75792 ribonuclease H2 subunit A Enzyme 4.2E-03 0.592 0.692
RIPK2 O43353 receptor interacting serine/threonine kinase 2 Kinase 0.39 0.587 0.769
PTPN12 Q05209 protein tyrosine phosphatase non-receptor type 12 1.00 0.641 0.769
PSMB8 P28062 proteasome 20S subunit beta 8 2.2E-02 0.533 0.808
PSTPIP1 O43586 proline-serine-threonine phosphatase interacting protein 1 Cellular structure 2.5E-06 0.650 0.577
PLCG2 P16885 phospholipase C gamma 2 Enzyme 1.00 0.588 0.808
OTULIN Q96BN8 OTU deubiquitinase with linear linkage specificity 0.22 0.751 0.346
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
NLRP12 P59046 NLR family pyrin domain containing 12 3.6E-28 0.569 0.846