Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
IL2 P60568 interleukin 2 0.48 0.336 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923