Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
IFNG | P01579 | interferon gamma | 0.47 | 0.288 | 0.962 | |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | |
NLRP3 | Q96P20 | NLR family pyrin domain containing 3 | 8.1E-04 | 0.361 | 0.962 | |
HLA-B | P01889 | major histocompatibility complex, class I, B | 3.9E-05 | 0.379 | 0.885 | |
IL1RN | P18510 | interleukin 1 receptor antagonist | 3.1E-02 | 0.373 | 0.923 | |
TNFRSF1A | P19438 | TNF receptor superfamily member 1A | 0.99 | 0.409 | 0.923 | |
CASP1 | P29466 | caspase 1 | Enzyme | 3.5E-05 | 0.413 | 0.885 |
NOD2 | Q9HC29 | nucleotide binding oligomerization domain containing 2 | Enzyme | 2.0E-30 | 0.423 | 0.923 |
MEFV | O15553 | MEFV innate immuity regulator, pyrin | 1.0E-14 | 0.440 | 0.885 | |
GLI3 | P10071 | GLI family zinc finger 3 | 1.00 | 0.436 | 0.846 | |
RIPK1 | Q13546 | receptor interacting serine/threonine kinase 1 | Kinase | 7.9E-03 | 0.479 | 0.769 |
TNFAIP3 | P21580 | TNF alpha induced protein 3 | Enzyme | 1.00 | 0.481 | 0.808 |
ADA2 | Q9NZK5 | adenosine deaminase 2 | Enzyme | 8.1E-08 | 0.545 | 0.846 |
NLRC4 | Q9NPP4 | NLR family CARD domain containing 4 | 9.9E-12 | 0.556 | 0.769 | |
MVK | Q03426 | mevalonate kinase | Kinase | 0.17 | 0.576 | 0.731 |
PAPPA | Q13219 | pappalysin 1 | 0.16 | 0.558 | 0.692 | |
NLRP12 | P59046 | NLR family pyrin domain containing 12 | 3.6E-28 | 0.569 | 0.846 | |
G6PC3 | Q9BUM1 | glucose-6-phosphatase catalytic subunit 3 | 4.7E-06 | 0.606 | 0.731 | |
WDR1 | O75083 | WD repeat domain 1 | Cellular structure | 1.00 | 0.623 | 0.654 |
PSTPIP1 | O43586 | proline-serine-threonine phosphatase interacting protein 1 | Cellular structure | 2.5E-06 | 0.650 | 0.577 |
IL36RN | Q9UBH0 | interleukin 36 receptor antagonist | 3.4E-08 | 0.638 | 0.538 | |
OTULIN | Q96BN8 | OTU deubiquitinase with linear linkage specificity | 0.22 | 0.751 | 0.346 |