Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
TNFRSF1A P19438 TNF receptor superfamily member 1A 0.99 0.409 0.923
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
GLI3 P10071 GLI family zinc finger 3 1.00 0.436 0.846
RIPK1 Q13546 receptor interacting serine/threonine kinase 1 Kinase 7.9E-03 0.479 0.769
TNFAIP3 P21580 TNF alpha induced protein 3 Enzyme 1.00 0.481 0.808
ADA2 Q9NZK5 adenosine deaminase 2 Enzyme 8.1E-08 0.545 0.846
NLRC4 Q9NPP4 NLR family CARD domain containing 4 9.9E-12 0.556 0.769
MVK Q03426 mevalonate kinase Kinase 0.17 0.576 0.731
PAPPA Q13219 pappalysin 1 0.16 0.558 0.692
NLRP12 P59046 NLR family pyrin domain containing 12 3.6E-28 0.569 0.846
G6PC3 Q9BUM1 glucose-6-phosphatase catalytic subunit 3 4.7E-06 0.606 0.731
WDR1 O75083 WD repeat domain 1 Cellular structure 1.00 0.623 0.654
PSTPIP1 O43586 proline-serine-threonine phosphatase interacting protein 1 Cellular structure 2.5E-06 0.650 0.577
IL36RN Q9UBH0 interleukin 36 receptor antagonist 3.4E-08 0.638 0.538
OTULIN Q96BN8 OTU deubiquitinase with linear linkage specificity 0.22 0.751 0.346