Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
VCP P55072 valosin containing protein 1.00 0.469 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
MFAP1 P55081 microfibril associated protein 1 Extracellular structure 0.80 0.431 0.846
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846