Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
EIF2AK3 Q9NZJ5 eukaryotic translation initiation factor 2 alpha kinase 3 Kinase 2.8E-03 0.501 0.808
KAT6B Q8WYB5 lysine acetyltransferase 6B Enzyme 1.00 0.525 0.731
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
GUSB P08236 glucuronidase beta 4.0E-08 0.530 0.846
LZTR1 Q8N653 leucine zipper like transcription regulator 1 1.0E-92 0.547 0.808
KIF22 Q14807 kinesin family member 22 Cellular structure 9.2E-10 0.552 0.654
RRAS P10301 RAS related Enzyme modulator 4.7E-03 0.543 0.808
RASA2 Q15283 RAS p21 protein activator 2 Enzyme modulator 7.4E-31 0.579 0.769
MRAS O14807 muscle RAS oncogene homolog Enzyme modulator 0.92 0.590 0.731
CCDC8 Q9H0W5 coiled-coil domain containing 8 0.25 0.599 0.692
A2ML1 A8K2U0 alpha-2-macroglobulin like 1 Enzyme modulator 1.6E-34 0.590 0.692
SOS2 Q07890 SOS Ras/Rho guanine nucleotide exchange factor 2 Enzyme modulator 1.00 0.608 0.692
CUL7 Q14999 cullin 7 2.6E-21 0.633 0.500
BMPER Q8N8U9 BMP binding endothelial regulator Enzyme modulator 6.6E-07 0.641 0.577
OBSL1 O75147 obscurin like cytoskeletal adaptor 1 1.0E-25 0.686 0.308
GPKOW Q92917 G-patch domain and KOW motifs Nucleic acid binding 1.00 0.722 0.462