Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
FANCD2 Q9BXW9 FA complementation group D2 1.1E-30 0.479 0.885
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
RECQL4 O94761 RecQ like helicase 4 Enzyme 3.3E-35 0.496 0.808
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
RAI1 Q7Z5J4 retinoic acid induced 1 Transcription factor 1.00 0.545 0.731
FLII Q13045 FLII actin remodeling protein 5.5E-12 0.520 0.808
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
AKT3 Q9Y243 AKT serine/threonine kinase 3 Kinase 1.00 0.512 0.808
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
DEAF1 O75398 DEAF1 transcription factor 3.4E-04 0.575 0.615
IQSEC2 Q5JU85 IQ motif and Sec7 domain ArfGEF 2 1.00 0.573 0.577
FANCF Q9NPI8 FA complementation group F 0.46 0.535 0.731
FANCI Q9NVI1 FA complementation group I 8.9E-37 0.543 0.731