Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
SLC2A1 | P11166 | solute carrier family 2 member 1 | Transporter | 0.99 | 0.388 | 0.808 |
GH1 | P01241 | growth hormone 1 | Signaling | 3.0E-02 | 0.373 | 0.923 |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
FGFR3 | P22607 | fibroblast growth factor receptor 3 | Kinase | 1.6E-05 | 0.391 | 0.846 |
MPO | P05164 | myeloperoxidase | Enzyme | 7.1E-15 | 0.377 | 0.923 |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
PLG | P00747 | plasminogen | Enzyme | 1.0E-02 | 0.389 | 0.923 |
FLNA | P21333 | filamin A | 1.00 | 0.419 | 0.846 | |
CDH1 | P12830 | cadherin 1 | 0.15 | 0.401 | 0.808 | |
WNK1 | Q9H4A3 | WNK lysine deficient protein kinase 1 | Kinase | 1.00 | 0.416 | 0.846 |
AVP | P01185 | arginine vasopressin | Signaling | 7.4E-02 | 0.437 | 0.846 |
CYP2D6 | P10635 | cytochrome P450 family 2 subfamily D member 6 | 1.1E-25 | 0.437 | 0.885 | |
TBX1 | O43435 | T-box transcription factor 1 | Transcription factor | 0.84 | 0.433 | 0.808 |
ATRX | P46100 | ATRX chromatin remodeler | 1.00 | 0.452 | 0.808 | |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
PGR | P06401 | progesterone receptor | Nuclear receptor | 5.1E-02 | 0.426 | 0.885 |