Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
LMNA P02545 lamin A/C 1.00 0.384 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
PTCH1 Q13635 patched 1 1.00 0.398 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808