Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
REN | P00797 | renin | Enzyme | 2.4E-07 | 0.370 | 0.923 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
GH1 | P01241 | growth hormone 1 | Signaling | 3.0E-02 | 0.373 | 0.923 |
FGFR3 | P22607 | fibroblast growth factor receptor 3 | Kinase | 1.6E-05 | 0.391 | 0.846 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
FBN1 | P35555 | fibrillin 1 | Calcium-binding protein | 1.00 | 0.417 | 0.846 |
GNAS | O95467 P63092 P84996 Q5JWF2 | GNAS complex locus | Enzyme modulator | 0.68 | 0.420 | 0.885 |
PTH | P01270 | parathyroid hormone | 1.2E-02 | 0.397 | 0.846 | |
COL2A1 | P02458 | collagen type II alpha 1 chain | 1.00 | 0.444 | 0.846 | |
CALR | P27797 | calreticulin | Calcium-binding protein | 0.89 | 0.413 | 0.923 |
SMAD3 | P84022 | SMAD family member 3 | Transcription factor | 0.80 | 0.415 | 0.923 |
SOX9 | P48436 | SRY-box transcription factor 9 | 1.00 | 0.419 | 0.846 | |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
BMP2 | P12643 | bone morphogenetic protein 2 | Signaling | 0.99 | 0.432 | 0.846 |
BMP4 | P12644 | bone morphogenetic protein 4 | Signaling | 0.96 | 0.422 | 0.808 |
NOTCH3 | Q9UM47 | notch receptor 3 | 0.41 | 0.435 | 0.808 |