Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
TERT | O14746 | telomerase reverse transcriptase | Enzyme | 0.99 | 0.374 | 0.846 |
MGMT | P16455 | O-6-methylguanine-DNA methyltransferase | 1.2E-07 | 0.412 | 0.885 | |
CDKN2B | P42772 | cyclin dependent kinase inhibitor 2B | 7.3E-03 | 0.417 | 0.769 | |
CDK4 | P11802 | cyclin dependent kinase 4 | Kinase | 6.3E-02 | 0.412 | 0.808 |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 |
BAP1 | Q92560 | BRCA1 associated protein 1 | Enzyme | 0.99 | 0.454 | 0.731 |
MITF | O75030 | melanocyte inducing transcription factor | 0.98 | 0.499 | 0.808 | |
MC1R | Q01726 | melanocortin 1 receptor | G-protein coupled receptor | 8.1E-11 | 0.524 | 0.808 |
MAP2K2 | P36507 | mitogen-activated protein kinase kinase 2 | Kinase | 0.97 | 0.534 | 0.731 |
TERF2IP | Q9NYB0 | TERF2 interacting protein | 2.7E-05 | 0.548 | 0.731 | |
SOX18 | P35713 | SRY-box transcription factor 18 | Transcription factor | 0.15 | 0.578 | 0.692 |
POT1 | Q9NUX5 | protection of telomeres 1 | Nucleic acid binding | 0.85 | 0.560 | 0.731 |
ACD | Q96AP0 | ACD shelterin complex subunit and telomerase recruitment factor | 1.1E-12 | 0.603 | 0.731 |