Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
PON1 | P27169 | paraoxonase 1 | 9.8E-11 | 0.409 | 0.885 | |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
DKK1 | O94907 | dickkopf WNT signaling pathway inhibitor 1 | 0.17 | 0.439 | 0.885 | |
PPARGC1A | Q9UBK2 | PPARG coactivator 1 alpha | Transcription factor | 1.00 | 0.453 | 0.885 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
ERBB4 | Q15303 | erb-b2 receptor tyrosine kinase 4 | Kinase | 1.00 | 0.455 | 0.846 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
FIG4 | Q92562 | FIG4 phosphoinositide 5-phosphatase | 2.3E-34 | 0.551 | 0.731 | |
TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 |
HNRNPA1 | P09651 | heterogeneous nuclear ribonucleoprotein A1 | 1.00 | 0.529 | 0.885 | |
ANG | P03950 | angiogenin | 0.29 | 0.511 | 0.769 | |
CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
OPTN | Q96CV9 | optineurin | 5.9E-18 | 0.548 | 0.808 | |
NEK1 | Q96PY6 | NIMA related kinase 1 | Kinase | 1.9E-25 | 0.575 | 0.769 |
NEFH | P12036 | neurofilament heavy | 2.7E-12 | 0.588 | 0.769 | |
PFN1 | P07737 | profilin 1 | 0.73 | 0.565 | 0.769 | |
EPHA4 | P54764 | EPH receptor A4 | Kinase | 1.00 | 0.566 | 0.846 |
PON2 | Q15165 | paraoxonase 2 | 5.4E-05 | 0.566 | 0.808 | |
DCTN1 | Q14203 | dynactin subunit 1 | Chaperone | 8.4E-02 | 0.597 | 0.500 |
CHCHD10 | Q8WYQ3 | coiled-coil-helix-coiled-coil-helix domain containing 10 | 5.4E-06 | 0.623 | 0.462 |