Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
CYP17A1 P05093 cytochrome P450 family 17 subfamily A member 1 2.6E-04 0.462 0.769
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
POR P16435 cytochrome p450 oxidoreductase 3.4E-10 0.502 0.769
SDHC Q99643 succinate dehydrogenase complex subunit C 2.0E-04 0.517 0.846
FSHR P23945 follicle stimulating hormone receptor G-protein coupled receptor 1.4E-11 0.539 0.654
CYP11B1 P15538 cytochrome P450 family 11 subfamily B member 1 8.2E-07 0.563 0.615
HSD3B2 P26439 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 Enzyme 7.2E-08 0.582 0.500
KLLN B2CW77 killin, p53 regulated DNA replication inhibitor 5.1E-03 0.578 0.654
CYB5A P00167 cytochrome b5 type A Enzyme 1.6E-03 0.601 0.654
SEC23B Q15437 SEC23 homolog B, COPII coat complex component Enzyme modulator 6.1E-20 0.579 0.692