Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
GRN P28799 granulin precursor 7.0E-02 0.435 0.846