Disease: Amyotrophic Lateral Sclerosis, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ALS2 Q96Q42 alsin Rho guanine nucleotide exchange factor ALS2 8.7E-12 0.647 0.423
ATXN1 P54253 ataxin 1 0.97 0.534 0.769
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CNTF P26441 ciliary neurotrophic factor 2.3E-05 0.561 0.615
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
HNRNPA1 P09651 heterogeneous nuclear ribonucleoprotein A1 1.00 0.529 0.885
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NEFH P12036 neurofilament heavy 2.7E-12 0.588 0.769
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
OPTN Q96CV9 optineurin 5.9E-18 0.548 0.808
PFN1 P07737 profilin 1 0.73 0.565 0.769
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PRPH P41219 peripherin 4.8E-14 0.623 0.462
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
STMN1 P16949 stathmin 1 7.5E-02 0.458 0.885
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
VAPB O95292 VAMP associated protein B and C Transporter 0.58 0.666 0.423