Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885
IL33 O95760 interleukin 33 8.3E-10 0.409 0.885
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
SETD2 Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 1.00 0.424 0.846
CD163 Q86VB7 CD163 molecule Enzyme 8.3E-04 0.427 0.846
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
JUN P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 6.0E-02 0.442 0.885
ZEB1 P37275 zinc finger E-box binding homeobox 1 Transcription factor 0.97 0.442 0.808