Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
MAPK1 | P28482 | mitogen-activated protein kinase 1 | Kinase | 1.00 | 0.330 | 0.923 |
MDM2 | Q00987 | MDM2 proto-oncogene | Nucleic acid binding | 1.00 | 0.362 | 0.846 |
HMGB1 | P09429 | high mobility group box 1 | Nucleic acid binding | 0.82 | 0.368 | 0.923 |
EPHB2 | P29323 | EPH receptor B2 | Kinase | 1.00 | 0.374 | 0.846 |
KDR | P35968 | kinase insert domain receptor | Kinase | 1.00 | 0.378 | 0.885 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
SLC2A1 | P11166 | solute carrier family 2 member 1 | Transporter | 0.99 | 0.388 | 0.808 |
LGALS3 | P17931 | galectin 3 | Signaling | 2.3E-05 | 0.392 | 0.846 |
COX8A | P10176 | cytochrome c oxidase subunit 8A | Enzyme | 0.12 | 0.400 | 0.846 |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
PDCD1 | Q15116 | programmed cell death 1 | 0.42 | 0.402 | 0.846 | |
LCN2 | P80188 | lipocalin 2 | Enzyme | 1.1E-09 | 0.405 | 0.885 |
IL33 | O95760 | interleukin 33 | 8.3E-10 | 0.409 | 0.885 | |
FOS | P01100 | Fos proto-oncogene, AP-1 transcription factor subunit | Transcription factor | 0.26 | 0.411 | 0.885 |
SETD2 | Q9BYW2 | SET domain containing 2, histone lysine methyltransferase | Epigenetic regulator | 1.00 | 0.424 | 0.846 |
CD163 | Q86VB7 | CD163 molecule | Enzyme | 8.3E-04 | 0.427 | 0.846 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
JUN | P05412 | Jun proto-oncogene, AP-1 transcription factor subunit | Transcription factor | 6.0E-02 | 0.442 | 0.885 |
ZEB1 | P37275 | zinc finger E-box binding homeobox 1 | Transcription factor | 0.97 | 0.442 | 0.808 |