Disease: Unipolar Depression
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
OXT P01178 oxytocin/neurophysin I prepropeptide Signaling 0.71 0.615 0.423
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
RGS4 P49798 regulator of G protein signaling 4 Enzyme modulator 5.1E-08 0.621 0.577
SYN2 Q92777 synapsin II Cellular structure 0.653 0.577
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
SLC1A1 P43005 solute carrier family 1 member 1 Transporter 8.7E-06 0.561 0.654
HCN1 O60741 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.00 0.564 0.654
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
FAAH O00519 fatty acid amide hydrolase 4.4E-11 0.545 0.692
PVALB P20472 parvalbumin Calcium-binding protein 8.7E-02 0.547 0.692
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769
EMP1 P54849 epithelial membrane protein 1 Cellular structure 0.50 0.560 0.769
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
GNB3 P16520 G protein subunit beta 3 Enzyme 3.3E-11 0.518 0.808
MDM4 O15151 MDM4 regulator of p53 Nucleic acid binding 1.00 0.461 0.808
ABCC1 P33527 ATP binding cassette subfamily C member 1 Transporter 1.2E-03 0.445 0.808
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808