Disease: Von Hippel-Lindau Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
F10 P00742 coagulation factor X Enzyme 2.3E-06 0.493 0.769
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
SDHC Q99643 succinate dehydrogenase complex subunit C 2.0E-04 0.517 0.846
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
PNMT P11086 phenylethanolamine N-methyltransferase Enzyme 5.0E-03 0.653 0.538
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
CHGA P10645 chromogranin A 3.0E-02 0.490 0.808
GCG P01275 glucagon 3.5E-02 0.431 0.885
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
SDHD O14521 succinate dehydrogenase complex subunit D Transporter 0.34 0.472 0.885
CGA P01215 glycoprotein hormones, alpha polypeptide 0.35 0.508 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
EPAS1 Q99814 endothelial PAS domain protein 1 Transcription factor 0.60 0.454 0.731
TIMP3 P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 0.63 0.445 0.923
MAX P61244 MYC associated factor X Transcription factor 0.83 0.553 0.769
NF1 P21359 neurofibromin 1 Enzyme modulator 0.90 0.440 0.885
MAZ P56270 MYC associated zinc finger protein 0.94 0.617 0.654
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885