Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
PRKAR1A | P10644 | protein kinase cAMP-dependent type I regulatory subunit alpha | 1.00 | 0.401 | 0.846 | |
PDGFRB | P09619 | platelet derived growth factor receptor beta | Kinase | 0.90 | 0.416 | 0.846 |
TRPV4 | Q9HBA0 | transient receptor potential cation channel subfamily V member 4 | Ion channel | 2.2E-16 | 0.457 | 0.808 |
NOTCH3 | Q9UM47 | notch receptor 3 | 0.41 | 0.435 | 0.808 | |
COL11A2 | P13942 | collagen type XI alpha 2 chain | 0.70 | 0.435 | 0.846 | |
GJB2 | P29033 | gap junction protein beta 2 | Cell-cell junction | 6.6E-16 | 0.441 | 0.846 |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
TYR | P14679 | tyrosinase | Enzyme | 5.0E-32 | 0.473 | 0.808 |
MAP3K7 | O43318 | mitogen-activated protein kinase kinase kinase 7 | Kinase | 1.00 | 0.477 | 0.808 |
MPZ | P25189 | myelin protein zero | 0.27 | 0.503 | 0.846 | |
PEX6 | Q13608 | peroxisomal biogenesis factor 6 | 6.3E-06 | 0.547 | 0.731 | |
RBP4 | P02753 | retinol binding protein 4 | Transporter | 0.52 | 0.493 | 0.808 |
CDH23 | Q9H251 | cadherin related 23 | 3.2E-06 | 0.539 | 0.769 | |
PROC | P04070 | protein C, inactivator of coagulation factors Va and VIIIa | Enzyme | 1.9E-05 | 0.504 | 0.808 |
ABCC6 | O95255 | ATP binding cassette subfamily C member 6 | Transporter | 5.6E-35 | 0.540 | 0.654 |
CYP24A1 | Q07973 | cytochrome P450 family 24 subfamily A member 1 | Enzyme | 3.2E-23 | 0.518 | 0.692 |
WNT10A | Q9GZT5 | Wnt family member 10A | Signaling | 4.2E-09 | 0.547 | 0.731 |
CDH2 | P19022 | cadherin 2 | 0.99 | 0.535 | 0.731 | |
CRPPA | A4D126 | CDP-L-ribitol pyrophosphorylase A | 2.5E-04 | 0.566 | 0.654 | |
PRRX1 | P54821 | paired related homeobox 1 | 0.24 | 0.543 | 0.769 | |
PEX14 | O75381 | peroxisomal biogenesis factor 14 | Receptor | 0.23 | 0.592 | 0.692 |
RPGRIP1 | Q96KN7 | RPGR interacting protein 1 | Enzyme modulator | 1.3E-23 | 0.553 | 0.654 |
LAMA3 | Q16787 | laminin subunit alpha 3 | Enzyme modulator | 8.8E-46 | 0.576 | 0.731 |