Disease: Idiopathic pulmonary hypertension
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
EDNRB P24530 endothelin receptor type B G-protein coupled receptor 9.2E-03 0.470 0.846
F2R P25116 coagulation factor II thrombin receptor G-protein coupled receptor 8.5E-03 0.444 0.846
F2RL1 P55085 F2R like trypsin receptor 1 G-protein coupled receptor 1.5E-04 0.480 0.769
GDF15 Q99988 growth differentiation factor 15 Signaling 3.0E-07 0.429 0.808
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
PDE5A O76074 phosphodiesterase 5A 1.1E-04 0.513 0.731
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PVR P15151 PVR cell adhesion molecule 3.9E-10 0.510 0.769
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
ST2 suppression of tumorigenicity 2 0.576 0.692
TGFBR3 Q03167 transforming growth factor beta receptor 3 3.1E-03 0.550 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962