Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
MAPK8 | P45983 | mitogen-activated protein kinase 8 | Kinase | 1.00 | 0.397 | 0.885 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
DNM1L | O00429 | dynamin 1 like | Enzyme modulator | 5.7E-04 | 0.475 | 0.808 |
UCHL1 | P09936 | ubiquitin C-terminal hydrolase L1 | Enzyme | 0.99 | 0.482 | 0.885 |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
PINK1 | Q9BXM7 | PTEN induced kinase 1 | Kinase | 1.9E-10 | 0.516 | 0.769 |
NR4A2 | P43354 | nuclear receptor subfamily 4 group A member 2 | Nuclear receptor | 1.00 | 0.529 | 0.846 |
SNCG | O76070 | synuclein gamma | Transporter | 8.5E-04 | 0.550 | 0.615 |
EIF4G1 | Q04637 | eukaryotic translation initiation factor 4 gamma 1 | Nucleic acid binding | 1.00 | 0.553 | 0.808 |
SNCB | Q16143 | synuclein beta | Transporter | 6.8E-02 | 0.619 | 0.577 |
CHCHD2 | Q9Y6H1 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 1.7E-07 | 0.638 | 0.538 | |
VPS35 | Q96QK1 | VPS35 retromer complex component | Transporter | 0.97 | 0.656 | 0.500 |
TMEM230 | Q96A57 | transmembrane protein 230 | 1.8E-04 | 0.769 | 0.115 | |
LRRK1 | Q38SD2 | leucine rich repeat kinase 1 | Kinase | 4.5E-10 | 0.780 | 0.115 |