Disease: Bradykinesia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
CHCHD2 Q9Y6H1 coiled-coil-helix-coiled-coil-helix domain containing 2 1.7E-07 0.638 0.538
FBXO7 Q9Y3I1 F-box protein 7 5.8E-07 0.650 0.769
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
SNCAIP Q9Y6H5 synuclein alpha interacting protein 3.3E-04 0.691 0.423
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
SPR P35270 sepiapterin reductase 4.3E-02 0.631 0.654
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
VPS35 Q96QK1 VPS35 retromer complex component Transporter 0.97 0.656 0.500
STX1B P61266 syntaxin 1B Transporter 0.99 0.650 0.308
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
NR4A2 P43354 nuclear receptor subfamily 4 group A member 2 Nuclear receptor 1.00 0.529 0.846
EIF4G1 Q04637 eukaryotic translation initiation factor 4 gamma 1 Nucleic acid binding 1.00 0.553 0.808
GIGYF2 Q6Y7W6 GRB10 interacting GYF protein 2 1.00 0.711 0.269