Disease: Lewy Body Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
MUL1 Q969V5 mitochondrial E3 ubiquitin protein ligase 1 1.9E-06 0.473 0.808
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846