Disease: PARKINSON DISEASE, LATE-ONSET
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
GAPDH P04406 glyceraldehyde-3-phosphate dehydrogenase Enzyme 0.11 0.447 0.808
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846