Disease: Obesity
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CYP2D7 A0A087X1C5 cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) 0.659 0.577
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
MIR126 microRNA 126 0.447 0.846
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
MOK Q9UQ07 MOK protein kinase Kinase 8.8E-22 0.476 0.769
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
CAST P20810 calpastatin 4.1E-12 0.541 0.846
P2RX7 Q99572 purinergic receptor P2X 7 Ion channel 3.3E-11 0.450 0.808
MC1R Q01726 melanocortin 1 receptor G-protein coupled receptor 8.1E-11 0.524 0.808
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
SMPD1 P17405 sphingomyelin phosphodiesterase 1 Enzyme 3.9E-10 0.499 0.885
NQO1 P15559 NAD(P)H quinone dehydrogenase 1 1.2E-09 0.434 0.885
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
MRPS30 Q9NP92 mitochondrial ribosomal protein S30 1.6E-08 0.590 0.731
SIRT2 Q8IXJ6 sirtuin 2 Epigenetic regulator 2.3E-08 0.510 0.769
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885
MTIF3 Q9H2K0 mitochondrial translational initiation factor 3 Nucleic acid binding 3.9E-07 0.890 0.115
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846