Disease: Progressive supranuclear palsy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
MAP2K4 P45985 mitogen-activated protein kinase kinase 4 Kinase 1.00 0.559 0.692
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
NAT2 P11245 N-acetyltransferase 2 Enzyme 3.3E-06 0.451 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
NR4A2 P43354 nuclear receptor subfamily 4 group A member 2 Nuclear receptor 1.00 0.529 0.846
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SNCAIP Q9Y6H5 synuclein alpha interacting protein 3.3E-04 0.691 0.423
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TH P07101 tyrosine hydroxylase 1.7E-06 0.462 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846