Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
COMT | P21964 | catechol-O-methyltransferase | Enzyme | 1.1E-06 | 0.400 | 0.923 |
DRD1 | P21728 | dopamine receptor D1 | G-protein coupled receptor | 0.96 | 0.529 | 0.808 |
DRD3 | P35462 | dopamine receptor D3 | G-protein coupled receptor | 2.4E-03 | 0.529 | 0.692 |
EIF4G1 | Q04637 | eukaryotic translation initiation factor 4 gamma 1 | Nucleic acid binding | 1.00 | 0.553 | 0.808 |
GBA | P04062 | glucosylceramidase beta | 1.4E-06 | 0.500 | 0.808 | |
GIGYF2 | Q6Y7W6 | GRB10 interacting GYF protein 2 | 1.00 | 0.711 | 0.269 | |
HTRA2 | O43464 | HtrA serine peptidase 2 | 3.6E-03 | 0.542 | 0.692 | |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
PINK1 | Q9BXM7 | PTEN induced kinase 1 | Kinase | 1.9E-10 | 0.516 | 0.769 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
SLC6A3 | Q01959 | solute carrier family 6 member 3 | Transporter | 1.00 | 0.453 | 0.885 |
SLC6A4 | P31645 | solute carrier family 6 member 4 | Transporter | 0.25 | 0.429 | 0.808 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
UCHL1 | P09936 | ubiquitin C-terminal hydrolase L1 | Enzyme | 0.99 | 0.482 | 0.885 |
VPS35 | Q96QK1 | VPS35 retromer complex component | Transporter | 0.97 | 0.656 | 0.500 |