Disease: Mental deterioration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CALB1 P05937 calbindin 1 Calcium-binding protein 0.24 0.606 0.615
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
FBXO7 Q9Y3I1 F-box protein 7 5.8E-07 0.650 0.769
GABPA Q06546 GA binding protein transcription factor subunit alpha Transcription factor 1.00 0.379 0.885
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
GBAP1 glucosylceramidase beta pseudogene 1 0.623 0.538
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885