Disease: Essential Tremor
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CHCHD2 Q9Y6H1 coiled-coil-helix-coiled-coil-helix domain containing 2 1.7E-07 0.638 0.538
CHM P24386 CHM Rab escort protein Enzyme 1.00 0.592 0.654
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
FGF20 Q9NP95 fibroblast growth factor 20 Signaling 0.81 0.663 0.577
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
LINGO1 Q96FE5 leucine rich repeat and Ig domain containing 1 Receptor 0.99 0.682 0.385
LRRK1 Q38SD2 leucine rich repeat kinase 1 Kinase 4.5E-10 0.780 0.115
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MC1R Q01726 melanocortin 1 receptor G-protein coupled receptor 8.1E-11 0.524 0.808
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
PARK3 Parkinson disease 3 (autosomal dominant, Lewy body) 0.821 0.038
PITX3 O75364 paired like homeodomain 3 0.81 0.585 0.692
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769